Researchers at Albert Einstein College of Medicine completed phase one clinical study of a griffithsin topical. This is designed to be applied as a gel to the vagina before sex to inhibit HIV infection. Phase one trials are done are to see what effect the pharmaceutical has on healthy humans. The results of this study are very promising, This is a huge step forward, and we look forward to the next phases of clinical trials.
Here's a link to the paper:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261775
Meanwhile our group is looking into what the optimal pH of a buffer for adhesion of DNA to W and AU microparticles would be. We would like to hear from anyone who has done particle bombardment on the subject of what buffers worked best.
